Breathe Technologies, Inc.    

Breathe Technologies is developing novel COPD therapy devices that are designed to significantly improve existing ventilation and supplemental oxygen therapy products, and provide dramatic quality of life benefits for COPD patients that require both assisted ventilation and oxygen therapy.   

Bioabsorbable Therapeutics, Inc.    

Bioabsorbable Therapeutics is using novel, proprietary polymers to create fully bioabsorbable stents for important medical applications. BTI has developed completely bioabsorbable stents that are inherently anti-inflammatory, addressing one of the main hurdles for such stents in cardiac applications.

Broncus Technology, Inc.

Broncus Technologies is focused on developing minimally invasive medical devices for lung diseases, including lung cancer and emphysema.  The Exhale® Drug-Eluting Stent is being investigated as the first minimally-invasive treatment option for homogeneous, or diffuse, emphysema.

Chestnut Medical, Inc.

Chestnut Medical is developing novel devices for interventional neuroradiology procedures.  The Company’s flagship product, the Pipeline aneurysm device, is a fine mesh tubular device that is used to isolate an aneurysm from blood flow without the need for coils. In June 2009 Chestnut Medical was acquired by ev3.

CV Ingenuity, Inc.

CV Ingenuity is developing drug eluting balloon and coating technology for use in peripheral and cardiac vascular interventional procedures to reduce the rate of restenosis.

EndoVx, Inc.

EndoVx is developing a novel noninvasive transesophageal vagal nerve ablation system using high intensity focused ultrasound, or HIFU, for the treatment of obesity.

InSite Medical, Inc.

InSite Medical is developing the Epiphany system for epidural access.  Using proprietary technology to provide highly controlled access to the epidural space, Epiphany can lower the risk for inadvertent damage to the delicate structures in this area.   

Promethean Surgical Devices, Inc.

Promethean Surgical Devices (PSD) is developing a unique pre-polymer technology platform into surgical adhesives and implantable devices to augment, replace or repair soft tissues for a broad range of surgical procedures. 

RetroVascular, Inc.

RetroVascular is developing a family of tools to allow the interventional cardiologist to treat chronic total occlusions, or CTOs, easily and rapidly, using a retrograde approach.

Spiracur, Inc.

Spiracur is developing a novel portable Negative Pressure Wound Therapy system, the SNaP, that provides significant advantages over other NPWT devices.

Uptake Medical, Inc.

Uptake Medical is developing a novel thermal vapor technology for minimally invasive lung volume reduction therapy in severe COPD and emphysema patients.   Uptake’s approach uses steam applied to the lung tissue using a catheter device delivered through a conventional bronchoscope.